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Basics
| Name | Luca Sala |
| Label | PhD |
| Summary | Scientist with expertise in cardiac cellular electrophysiology, human induced pluripotent stem cell (hiPSC) technology, and precision medicine. Research activity focuses on disease modelling of inherited cardiac diseases, development of advanced electrophysiological technologies for phenotypic screening, and identification of novel therapeutic strategies for congenital and acquired arrhythmias, with a commitment to new approach methodologies (NAMs) as complementary methods to animal models. |
Work
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2025 - Present Milan, Italy
Junior PI, Laboratory of Cardiovascular Genetics
Istituto Auxologico Italiano IRCCS
Center for Cardiac Arrhythmias of Genetic Origin, Director: Peter J. Schwartz
- Leading cellular electrophysiology and drug screening on iPSCs
- Investigating genotype-phenotype relationships in cardiac channelopathies
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2022 - 2025 Milan, Italy
Assistant Professor of Physiology (RTD-A)
University of Milano - Bicocca
Department of Biotechnology and Biosciences
- Investigating the reasons behind incomplete penetrance and variable expressivity in congenital Long QT Syndrome
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2018 - 2025 Milan, Italy
Affiliated Researcher
Istituto Auxologico Italiano IRCCS
Center for Cardiac Arrhythmias of Genetic Origin, Director: Peter J. Schwartz
- Patient-specific disease model for congenital and acquired cardiac disorders
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2015 - 2017 Leiden, The Netherlands
Postdoctoral Fellow
Leiden University Medical Center (LUMC)
Department of Anatomy & Embryology, Supervisor: Prof. Christine L. Mummery
- Development of MUSCLEMOTION software for cardiac contraction analysis
- hERG allosteric modulator for Long QT Syndrome rescue
Education
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2011 - 2014 Milan, Italy
PhD
University of Milano - Bicocca
Molecular and Translational Medicine
- Thesis: Cardiac arrhythmias of genetic origin modelled with human induced pluripotent stem cells (hiPSCs)
- Supervisor: Prof. Antonio Zaza
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2009 - 2011 Milan, Italy
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2006 - 2009 Milan, Italy
Awards
- 2022
Junior PI Grant - NextGenerationEU (MSCA-IF)
NextGenerationEU
Funding for research on cardiac arrhythmias caused by ion channel trafficking defects
- 2022
Abilitazione Scientifica Nazionale
Italian Ministry of University
National Scientific Qualification for Associate Professorship in Physiology (05/D1)
- 2021
Early Career Grant - CARIPLO Foundation
CARIPLO Foundation
Biomedical Research Conducted By Young Researchers
- 2018
EU H2020 Marie Skłodowska-Curie Individual Fellowship
European Commission
PREMED-CARE: Precision Medicine with iPSCs for Cardiac Arrhythmias Risk Evaluation
Skills
| Stem Cell Biology | |
| Human induced pluripotent stem cells | |
| Cardiac Differentiation | |
| Disease Modelling |
| Cellular Electrophysiology | |
| Patch Clamp | |
| MultiElectrode Arrays | |
| Dynamic Clamp | |
| Ion Imaging |
| Cardiology | |
| Cardiac Arrhythmias | |
| Channelopathies | |
| Cardiomyopathies | |
| Sudden Cardiac Death |
| Software tools | |
| MUSCLEMOTION | |
| BAPTA | |
| Python scripts | |
| R scripts |
Languages
| Italian | |
| Native speaker |
| English | |
| Fluent |